Center For Novel Approaches in Hearing Loss Research
The House Institute Foundation’s Center for Novel Approaches in Hearing Loss Research performs groundbreaking research, pioneering new treatments for patients with hearing loss. Our commitment to curing hearing loss means that we are constantly exploring new frontiers in research, pushing boundaries of hearing science, developing novel approaches, and crafting solutions that hold the potential to revolutionize patient care.
About Hearing Loss
Hearing loss affects over half a billion people worldwide, and unfortunately, there are no FDA-approved drug therapies and diagnostic capabilities remain limited. For many, hearing aids are suboptimal, and while cochlear implants can help, they still do not restore perfect hearing. This is why our Center exists—to address these challenges and provide effective solutions for those with hearing loss. If you or a loved one need assistance, please do not hesitate to contact us at (213)-483-9930 for clinic appointments.
Areas of Research
The House Institute Foundation’s Center for Novel Approaches in Hearing Loss Research includes many topics that are being actively explored, such as:
Sensorineural Hearing Loss (SNHL)
Sensorineural hearing loss (SNHL) is a critically important condition to address due to its significant impact on an individual’s ability to hear and communicate. SNHL occurs when there is damage to the inner ear or the auditory nerve, which is responsible for transmitting sound signals from the ear to the brain. At HIF, we prioritize the treatment of SNHL because of its complex nature and the urgent need for advanced diagnostic tools and therapeutic solutions. By focusing on this condition, we aim to offer patients the latest in research, technology, and specialized care to improve their hearing and, ultimately, their ability to live a more fulfilling life.
Hearing Diagnostic Biomarker Initiative
Currently, there are limited non-audiometric tests available for diagnosing hearing loss, which is why we are actively working to develop new, innovative diagnostic tools. One promising approach is proteomics, the study of proteins that are essential for cellular function and play key roles in various diseases. By leveraging proteomics, we aim to create more effective ways to diagnose hearing loss and improve patient outcomes.
Novel Clinical Trials
1. Tympanic Membrane Perforation
a. A multicenter, prospective, open-label clinical trial to evaluate the safety and effectiveness of the Perf-Fix Otologic Gel Patch to aid in the repair of chronic tympanic membrane perforation
b. Assessing efficacy of novel non-surgical treatment for tympanic membrane perforation.
c. Seeking patients with tympanic membrane perforation >25% that is not actively healing